Since developing causation through experimental trials was impossible on account of moral restrictions, a lengthy review was performed if you want to establish the strong association important to let for legislative action towards smoking cigarettes tobacco.[citation wanted] In cigarette smoking, long-term exposure to compounds found in the smoke (e.g., https://holdenvqkzq.onesmablog.com/the-fact-about-tabacco-that-no-one-is-suggesting-74678495