Abstract The inability of adult human cardiomyocytes to proliferate is an obstacle to efficient cardiac regeneration after injury. Understanding the mechanisms that drive postnatal cardiomyocytes to switch to a non-regenerative state is therefore of great significance. Here we show that Arid1a. a subunit of the switching defective/sucrose non-fermenting (SWI/SNF) chromatin remodeling ... https://www.roamingfreesims.com/product-category/t12-led-replacement/
Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation
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